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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3HC1
All Species:
22.73
Human Site:
T235
Identified Species:
45.45
UniProt:
Q86WB0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WB0
NP_057562.3
502
55262
T235
R
T
D
E
R
K
T
T
I
K
L
G
S
D
I
Chimpanzee
Pan troglodytes
XP_001156206
502
55199
T235
R
T
D
E
R
K
T
T
I
K
L
G
S
D
I
Rhesus Macaque
Macaca mulatta
XP_001094530
502
55199
T235
R
T
D
E
R
K
T
T
I
K
L
G
S
D
I
Dog
Lupus familis
XP_532428
589
65257
T322
R
T
E
E
R
K
T
T
S
K
L
G
S
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80YV2
501
55178
T235
H
A
D
D
R
K
T
T
S
K
L
G
S
D
V
Rat
Rattus norvegicus
NP_001120765
501
55306
T235
Q
I
D
D
R
K
T
T
S
K
L
G
S
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510194
625
67731
A294
R
T
D
G
D
R
A
A
V
K
L
G
S
D
I
Chicken
Gallus gallus
XP_414975
484
53210
H219
L
I
K
E
E
L
E
H
R
T
E
G
E
K
P
Frog
Xenopus laevis
Q6P7H4
477
53273
L213
T
V
S
R
L
L
R
L
I
E
D
E
L
K
P
Zebra Danio
Brachydanio rerio
NP_001070846
492
54140
S226
A
K
Q
G
S
S
P
S
K
V
S
S
D
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200598
300
33790
P38
E
Q
S
S
T
V
Q
P
L
N
Q
E
L
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141693
698
76497
Y272
A
F
Q
D
A
D
T
Y
Y
Q
A
L
K
I
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
79.2
N.A.
85
85.8
N.A.
53.4
62.3
52.1
43
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.1
99
81.4
N.A.
91
91.2
N.A.
63.3
74.5
65.3
61.9
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
60
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
73.3
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
9
0
9
9
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
25
9
9
0
0
0
0
9
0
9
59
0
% D
% Glu:
9
0
9
42
9
0
9
0
0
9
9
17
9
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
9
% F
% Gly:
0
0
0
17
0
0
0
0
0
0
0
67
0
0
0
% G
% His:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
34
0
0
0
0
9
59
% I
% Lys:
0
9
9
0
0
50
0
0
9
59
0
0
9
17
0
% K
% Leu:
9
0
0
0
9
17
0
9
9
0
59
9
17
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
9
0
0
0
0
0
9
17
% P
% Gln:
9
9
17
0
0
0
9
0
0
9
9
0
0
0
0
% Q
% Arg:
42
0
0
9
50
9
9
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
17
9
9
9
0
9
25
0
9
9
59
0
0
% S
% Thr:
9
42
0
0
9
0
59
50
0
9
0
0
0
0
0
% T
% Val:
0
9
0
0
0
9
0
0
9
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _